Agilent Technologies G1978B setup guide To setup a method to use the multimode source

Models: G1978B

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To setup a method to use the multimode source

To setup a method to use the multimode source

To have your method use a multimode source, follow these steps:

1Open the MSD Spray Chamber dialog box by clicking Instrument > MSD Spray Chamber in the Method and Run Control view.

2Set Method Spray Chamber to MM-ES+APCI.

3Verify that Installed Spray Chamber is set to MM-ES+APCI.

4Make any other changes that are necessary for your method.

5Click the OK button.

6Open The Set up MSD Signals dialog box by clicking Instrument > More > Set up MSD Signals in the Method and Run Control view.

7Choose the desired ionization mode from the Ionization list. This list is only visible if the Method Spray Chamber was set to MM-ES+APCI. You may set the ionization mode to one of the following:

MM-ES

MM-APCI

MM-ES+APCI

8Make any other changes that are necessary for your method.

9Click the OK button.

WA R N I N G

The 6100 Series Single Quad LC/MS Liquid Chromatograph diverter valve is an

integral part of the G1978B safety system. The LC mobile phase flow must always be

 

 

connected to the diverter valve inlet filter. Never bypass the diverter valve and

 

connect directly to the nebulizer. If the diverter valve is used in a manner not

 

specified by Agilent Technologies, the protections provided by the diverter valve may

 

be impaired and the system may catch fire.

 

 

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Multimode Source for 6100 Series Single Quad LC/MS Set-Up Guide

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Agilent Technologies G1978B To setup a method to use the multimode source, Be impaired and the system may catch fire

G1978B specifications

Agilent Technologies G1978B is a high-performance mass spectrometer that is widely recognized for its innovations in analytical chemistry. This instrument stands out due to its combination of advanced technologies that enhance sensitivity, accuracy, and precision for complex analyses.

One of the key features of the G1978B is its compatibility with various ionization techniques, including Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI). This versatility allows users to analyze a diverse range of sample types, from small molecules to large biomolecules. Each ionization technique has its unique advantages, making the G1978B an excellent choice for laboratories focusing on pharmaceuticals, environmental analysis, and proteomics.

The G1978B is equipped with a sophisticated quadrupole mass filter, ensuring high-resolution mass measurements. This technology provides excellent mass accuracy and reproducibility, enabling users to distinguish between closely related compounds with minimal interference. The advanced data acquisition systems incorporated in the G1978B allow for rapid scanning capabilities, making it particularly effective for high-throughput screening applications.

In addition, the instrument features an intuitive user interface that simplifies method development and operational tasks. This includes streamlined software solutions that facilitate data analysis and interpretation, ensuring that even complex datasets can be managed efficiently. Furthermore, built-in diagnostic tools help in monitoring instrument performance, significantly reducing downtime and enhancing productivity.

The G1978B also incorporates advanced technologies for enhanced sensitivity. Its innovative source design minimizes background noise while maximizing signal intensity, making it particularly valuable for the detection of trace-level contaminants or low-abundance metabolites. Coupled with its exceptional dynamic range, the G1978B can quantify analytes over several orders of magnitude, which is crucial for applications in toxicology and clinical research.

With a robust design and ease of integration into existing laboratory workflows, the Agilent G1978B provides an ideal solution for researchers seeking a reliable mass spectrometry platform. Its combination of advanced ionization techniques, high-resolution capabilities, and user-friendly software makes it a versatile tool in modern analytical laboratories, paving the way for breakthroughs in research and development across a multitude of scientific disciplines.