Agilent Technologies G1978B setup guide To convert from multimode to ESI, Apci or Appi

Models: G1978B

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1Installation

To convert from multimode to ESI, APCI or APPI

10 Place the source shipping cover on the source.

To convert from multimode to ESI, APCI or APPI

WA R N I N G

Never touch the source surfaces, especially when you analyze toxic substances or

when you use toxic solvents. The source has several sharp pieces which can pierce

 

 

your skin including the APCI corona needle, vaporizer sensor and counter current

 

electrode.

 

 

 

 

1

If the source to be installed is an APPI source, disconnect the multimode

 

 

high voltage PCA RS-232 serial cable from the serial port B connector of

 

 

Smart Card.

 

2

Unscrew and remove the multimode spray shield with the field shaping

 

 

electrodes.

 

3

Install the new source and the standard spray shield, making sure that the

 

 

hole in the spray shield is in the 12 o'clock position.

 

4

For APCI and APPI ion source, connect the vaporizer heater cable and the

 

 

APCI high voltage cable. For the APPI source, connect the RS-232 cable to

 

 

the serial port B connector of Smart Card.

 

5

For all sources, reconnect the nebulizer gas line tubing and the LC/MS

 

 

sample tubing.

14

Multimode Source for 6100 Series Single Quad LC/MS Set-Up Guide

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Agilent Technologies G1978B setup guide To convert from multimode to ESI, Apci or Appi

G1978B specifications

Agilent Technologies G1978B is a high-performance mass spectrometer that is widely recognized for its innovations in analytical chemistry. This instrument stands out due to its combination of advanced technologies that enhance sensitivity, accuracy, and precision for complex analyses.

One of the key features of the G1978B is its compatibility with various ionization techniques, including Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI). This versatility allows users to analyze a diverse range of sample types, from small molecules to large biomolecules. Each ionization technique has its unique advantages, making the G1978B an excellent choice for laboratories focusing on pharmaceuticals, environmental analysis, and proteomics.

The G1978B is equipped with a sophisticated quadrupole mass filter, ensuring high-resolution mass measurements. This technology provides excellent mass accuracy and reproducibility, enabling users to distinguish between closely related compounds with minimal interference. The advanced data acquisition systems incorporated in the G1978B allow for rapid scanning capabilities, making it particularly effective for high-throughput screening applications.

In addition, the instrument features an intuitive user interface that simplifies method development and operational tasks. This includes streamlined software solutions that facilitate data analysis and interpretation, ensuring that even complex datasets can be managed efficiently. Furthermore, built-in diagnostic tools help in monitoring instrument performance, significantly reducing downtime and enhancing productivity.

The G1978B also incorporates advanced technologies for enhanced sensitivity. Its innovative source design minimizes background noise while maximizing signal intensity, making it particularly valuable for the detection of trace-level contaminants or low-abundance metabolites. Coupled with its exceptional dynamic range, the G1978B can quantify analytes over several orders of magnitude, which is crucial for applications in toxicology and clinical research.

With a robust design and ease of integration into existing laboratory workflows, the Agilent G1978B provides an ideal solution for researchers seeking a reliable mass spectrometry platform. Its combination of advanced ionization techniques, high-resolution capabilities, and user-friendly software makes it a versatile tool in modern analytical laboratories, paving the way for breakthroughs in research and development across a multitude of scientific disciplines.