Agilent Technologies G1978B setup guide Methods

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Agilent G1978B Multimode Source for 6100 Series Single Quad LC/MS

Set-Up Guide

3 Methods

To setup a method to use the multimode source 36

To create a method for positive/negative mixed mode operation 37

To create a method for alternating ESI and APCI operation 39

This chapter describes the tasks that you need to set up methods for the multimode source. See “Guidelines” in the Agilent G1978A/B Multimode Source Maintenance Guide for suggested source conditions for the multimode source for the different ionization modes.

Agilent Technologies

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Contents Set-Up Guide U T I O N WA R N I N G This Guide Page Content Contents Installation Prepare to install InstallationFrom left to right G1946-80058, G1960-60802 and G1960-60856 Install the HV control PCA and cablesConnecting the valve PCA to the multimode HV power supply Connecting the Vcap and Vchamber cables to the power supply Connecting the HV PCA to the chassis To remove the multimode source Changing SourcesTo convert from multimode to ESI, Apci or Appi To convert from ESI, Apci or Appi to the multimode source Installation onStandard spray shield and capillary cap for ESI or Apci T E Multimode Spray Chamber No nebulizer on top of the multimode source LC/MS sample tubing connected to LC/MS inlet filter Verification Preparation 6110 and 6120 Quad Performance Verification Summary Table 6140 Quad Performance Verification Summary, SIM Mode 20 1 pk-pk 10 1 pk-pk Verification 6140 Quad Performance Verification Summary, Scan Mode 6130SCNESMM.M 6130SCNCIMM.M Verification Create and run a Multiple FIA Method Sequence Verification Autotune report To do an autotuneExample of multimode verification report Example of multimode verification report Methods Be impaired and the system may catch fire To setup a method to use the multimode sourceMethods Polarity options for Signal 1 and Signal Method Spray Chamber set to MM-ES+APCI To create a method for alternating ESI and Apci operationIonization mode for Signal 1 and Signal Index Index Page G1978-90070