B-18 Appendix B—Serial Interface

If the printer does not respond at all to the host:

Make sure that you have selected "Serial" under "Active Interface" in the configuration menu. [Also, do not forget that the printer's "Serial Options" (protocol, baud, parity, and so on) must match those of the computer.]

Check that Pin 3, RxD, on the printer is connected to TxD on the computer (Pin 2 on a PC; Pin 3 on a PC/AT). If true, connect DTR, Pin 20, on the PC to DCD, Pin 8, on the PC to initiate transmission.

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Epson 4100 manual