Sharp AR-M208 Stability And Reactivity, Toxicological Information, Ecological Information

Models: AR-M208

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10. STABILITY AND REACTIVITY

10. STABILITY AND REACTIVITY

Stability

:

Stable

Hazardous Reactions

:

Dust explosion, like most finely divided organic powders.

Conditions to avoid

:

Electric discharge, throwing into fire.

Materials to avoid

:

Oxidizing Materials

Hazardous Decomposition Products :

CO, CO2 and NOx

Further Information

:

None

11. TOXICOLOGICAL INFORMATION

Acute Toxicity

 

 

Ingestion(oral)

:

LDL50>2500mg/kg (Rats)

Dermal

:

No Data

Inhalation

:

No Data

Eye irritation

:

Not an irritant (Rabbits)

Skin irritation

:

Not an irritant (Rabbits)

Skin sensitizer :

No Data

Mutagenicity

:

Negative (Ames Test)

Carcinogenicity

:

In 1996 the IARC reevaluated carbon black as a Group 2B carcinogen (possible human

 

 

carcinogen). This classification is given to chemicals for which there is inadequate human

 

 

evidence, but sufficient animal evidence on which to base an opinion of carcinogenicity. The

 

 

classification is based upon the development of lung tumors in rats receiving chronic

 

 

inhalation exposures to free carbon black at levels that induce particle overload of the lung.

 

 

Studies performed in animal models other than rats did not show any association between

 

 

carbon black and lung tumors. Moreover, a two-year cancer bioassay using a typical toner

 

 

preparation containing carbon black demonstrated no association between toner exposure

 

 

and tumor development in rats.

Chronic Effect

:

In a study in rats of chronic inhalation exposure to a typical toner, a mild to moderate degree

 

 

of lung fibrosis was observed in 92% of the rats in the high concentration (16mg/m3)

exposure group, and a minimal to mild degree of fibrosis was noted in 22% of the animals in the middle (4mg/m3) exposure group, but no pulmonary change was reported in the lowest (1mg/m3) exposure group, the most relevant level to potential human exposures.

12. ECOLOGICAL INFORMATION

No data are available.

13. DISPOSAL CONSIDERATION

Waste from residues

: Waste material may be dumped or incinerated under conditions which meet all

 

federal, state and local environmental regulations.

Contaminated Packaging : Waste may be disposed or incinerated under conditions which meet all federal, state

 

 

 

and local environmental regulations.

 

14. TRANSPORT INFORMATION

UN Classification

:

None

Land

DOT (USA)

:

None

Sea

IMDG

:

None

Air

ICAO-TI

:

None

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Sharp AR-M208 Stability And Reactivity, Toxicological Information, Ecological Information, Disposal Consideration