Chromatographic Troubleshooting
Troubleshooting valve systems
Troubleshooting valve systems
Chromatographic symptoms
Troubleshooting valves and their related plumbing is primarily a matter of systematic checking and verification of unimpaired mechanical operation of any moving part. This requires an understanding of how the valve functions internally and how the plumbing is configured. A plumbing diagram is essential for effective troubleshooting.
The following symptom•causelist gives the most commonly encountered problems and solutions found with valves.
Loss of sensitivity or excessive drift
Several possible causes exist for overall deterioration of the chromatogram.
CContamination in the valve requires a thorough cleaning.
CInternal leakage necessitates a complete disassembly and inspection of the mating surfaces.
CPoor temperature control may require a full check of electronic and thermal components.
CLack of proper conditioning techniques, columns, etc.
CFailure or deterioration of other components (i.e., columns, detectors, etc.).
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