should work fine with most drives. Changing this setting is not recommended unless some particular bus signal issues occur.

All SATA/ATA-based system connects only one drive per SATA/ATA channel. This helps to avoid single drive failure from affecting other drives. The maximum mechanical performance of today’s drives can reach around 30MB/sec (sustained read). This is still far below the bandwidth of a drive channel bus. Setting the SATA/ATA bus speed to a lower value can get around some problems, but will not become a bottleneck to system performance.

Mind that the SATA/ATA speed is the maximum transfer rate of SATA/ATA bus in that mode. It does not mean the drive can actually carry out that amount of sustained read/write performance. For the performance of each drive model, please refer to the documentation provided by drive manufacturer.

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Infortrend

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Compaq Infortrend manual