Process that Occurs During Peak Detection, Centroiding, and Integration

3.6Process that Occurs During Peak Detection, Centroiding, and Integration

This section gives an overview of the process that occurs during peak detection, centroiding and integration. Parameters are defined in detail in Section 3.2.4, Peak Detection Parameter Descriptions.

Peak detection During peak detection, the Data Explorer software:

 

• Divides the trace into detection ranges based on the

 

number of data points per peak (described in

 

 

Section 3.1.2, The Resolution-Based Peak Detection

 

Routine).

 

• Starts scanning the chromatogram or spectrum at the

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origin of the x-axis.

• Applies a Gaussian sliding filter to the number of raw data

 

points defined by the Filter Width setting. The filter moves

 

across the raw data by the number of data points

 

specified by the Increment parameter. An Increment of 1

 

 

is used for chromatogram data.

 

• Searches for an upward-to-downward inflection point

 

greater than the larger of the two specified peak detection

 

thresholds (% Base Peak Intensity or Minimum Intensity).

 

A Minimum Intensity of 2 is used for chromatogram data.

 

This inflection point defines the apex region.

 

• After the apex region is identified, scans to find the

 

downward-to-upward inflection points. These downward

 

to upward inflection points are the valley regions of the

 

peak.

 

Data Explorer™ Software User’s Guide

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